Category: Probiotics & Prebiotics

Saccharomyces boulardii is a probiotic yeast which nutritionally supports the health of the gastrointestinal tract. This yeast supports a balance of healthy gut flora.

Lactobacillus rhamnosus GG is one of the most characterized and utilized probiotic strains, with numerous clinical trials across all ages. It is a human origin strain, identified for its resistance to gastric acidity, adhesion properties, and ability to support healthy gut microflora. Studies involving infants and children suggest that supplementation with L. rhamnosus GG supports healthy G.I. colonization, G.I. function, and immune function, particularly related to skin and respiratory health. In a study involving children ages 1-7 attending day care, L. rhamnosus GG offered statistically significant support for respiratory and immune health. Studies involving pregnant women suggest supplementation supports healthy gut microflora in the infant, and nutrient metabolism during pregnancy. In one study, infants whose mothers had received L. rhamnosus GG during pregnancy showed increased bifidobacterial diversity at Day 5 after birth. L. rhamnosus GG is well known for its effects on bowel function, particularly abdominal comfort, bowel motility and occasional diarrhea. It also promotes cytokine balance in the G.I. tract at the level of gene expression, and overall immunomodulatory support. In a double-blind, crossover study, L. rhamnosus GG supplementation moderated the neutrophil and monocyte immune response in dairy-challenged, milk-sensitive subjects, while promoting immune function in non-sensitive subjects. In another study, L. rhamnosus GG promoted healthy gene expression to support white blood cell (WBC) function. Elderly subjects supplemented for 28 days showed 95 differentially expressed genes related to cellular movement, cell-to-cell signaling, and cytokine response.

PureProbiotic (allergen-free) contains a blend of beneficial probiotic microorganisms derived from fermentation on a dairy-free, soy-free medium to ensure tolerability in individuals with food allergies or sensitivities. Each capsule provides 5 billion CFU per capsule of Lactobacillus acidophilus, Lactobacillus plantarum, Lactobacillus rhamnosus, Bifidobacterium bifidum, Bifidobacterium lactis and Bifidobacterium breve to support immune and gastrointestinal health. Research indicates that these strains promote healthy microflora balance, G.I. integrity, bowel regularity and healthy immune cell function in children and adults.

Probiotic support for healthy intestinal microflora in powder form
• For children ages 1 and up
• For daily use
• Dairy and soy-free blend of Lactobacillus acidophilus, Bifidobacterium bifidum and Bifidobacterium lactis (formerly known as Bifidobacterium infantis)
• Supports the mucosal lining of the G.I. tract and healthy G.I. barrier function
• Maintains healthy immune system function
• Promotes intestinal comfort

Probiotic 50B provides 50 billion CFU of the beneficial bacteria Lactobacillus acidophilus, Lactobacillus rhamnosus, Lactobacillus plantarum, Bifidobacterium longum and Bifidobacterium lactis in acid-resistant capsules with pH targeted release to deliver maximal viable organisms to the digestive tract. These five researched strains promote healthy intestinal ecology to support gastrointestinal and immune health. Clinical studies indicate that lactobacilli and bifidobacteria supplementation supports intestinal epithelial integrity and healthy immune response.

Probiotic G.I. provides 10 billion CFU per capsule of the beneficial bacteria Lactobacillus acidophilus, Lactobacillus salivarius, Lactobacillus casei, Bifidobacterium bifidum, Bifidobacterium lactis and Streptococcus thermophilus. Research indicates that these strains provide particular support for healthy immune balance within the G.I. tract. Beneficial microflora are crucial for proper gut associated lymphoid tissue (GALT) function and development. The GALT helps protect intestinal mucosa from allergens and toxins and is a major component of the body’s immune system. It is estimated that more than 70% of the body’s B lymphocytes are found in the GALT. Probiotics are believed to support healthy GALT composition, and in turn, support barrier function, G.I. epithelial cell health and T cell function within the G.I. tract. Some probiotic strains may also modulate local production of cytokines in the G.I. epithelium. B. lactis supports healthy T cell activity and cytokine production in the intestine, at least in part by regulating transcription of genes that encode for cytokines. L. acidophilus promotes healthy cytokine production in the colon. Research also suggests that metabolites produced from Streptococcus thermophilus may cross the intestinal barrier to support healthy cytokine production and immune function.

A meta-analysis involving 9 randomized controlled trials has revealed that probiotics maintain healthy immune and nasal function. Probiotic IMM provides 5 billion CFU per serving of the beneficial bacteria Bifidobacterium longum BB536, Bifidobacterium lactis, Lactobacillus acidophilus, Lactobacillus casei and Lactobacillus plantarum. These strains provide particular support for a healthy immune response and immunoglobulin function. B. longum BB536 is a shelf stable, top-selling probiotic in Japan, supported in the literature by over 25 human trials and 30 animal studies. Double-blind, placebo-controlled trials indicate that B. longum BB536 supplementation maintains G.I. bacteria balance, supporting immune function and maintaining eye, nose and throat health. In another randomized double-blind, placebo-controlled trial, L. acidophilus and B. lactis showed support for nasal function and maintained healthy eosinophil activity within the nasal lining. Research involving L. casei and L. plantarum also suggests that these strains maintain healthy cytokine production, IgE function and mast cell integrity.

This dairy and soy-free formula provides 10 billion CFU of the beneficial bacteria Lactobacillus acidophilus, Lactobacillus rhamnosus, Bifidobacterium longum, Bifidobacterium bifidum and Bifidobacterium lactis. L. acidophilus and B. longum have been shown to promote healthy cytokine production in the colon and maintain healthy G.I. barrier function, in part by supporting the mucosal lining of the G.I. tract. Several trials have also revealed that mixed probiotic supplementation helps maintain intestinal flora, support healthy yeast balance, and promote G.I. comfort. A study involving elderly individuals indicated that a mixture of lactobacilli and bifidobacteria maintained healthy gut ecology. Studies also suggest that probiotics support immune health, enhancing B cell, T cell and NK cell function.

PureBi•Ome G.I. offers four clinically-researched probiotic strains, Lactobacillus acidophilus (NCIMB 30157), Lactobacillus acidophilus (NCIMB 30156), Bifidobacterium bifidum (NCIMB 30153) and Bifidobacterium lactis (NCIMB 30172), combined with l-glutamine to support microflora balance and gastrointestinal (G.I.) function. The 4-strain blend is the focus of numerous clinical trials, showing support for healthy microflora, bowel function, and GI comfort. l-Glutamine is a conditionally essential amino acid utilized by the body for tissue repair, gastrointestinal tract support, and natural defense system function in times of metabolic stress. In studies, glutamine supplementation supports intestinal integrity and barrier function.

PureBi•Ome Intensive offers 25 billion CFU per capsule of four clinically- researched probiotic strains, Lactobacillus acidophilus (NCIMB 30157), Lactobacillus acidophilus (NCIMB 30156), Bifidobacterium bifidum (NCIMB 30153) and Bifidobacterium lactis (NCIMB 30172), combined with 5 billion CFU Saccharomyces boulardii. The 4-strain blend is the focus of numerous clinical trials, showing support for healthy microflora, bowel function, and GI comfort. Saccharomyces boulardii is included as additional support for healthy bowel function. In a double-blind, controlled trial involving 151 individuals, S. boulardii supplementation lessened the occurrence of occasional diarrhea and supported overall bowel health. Research suggests that S. boulardii may stimulate enzyme secretions to support normal digestive functions and neutralize toxins for a healthy G.I. tract.